Devising methods and reagents for stereoselective synthesis is an intellectually demanding venture. Six experts on diastereo- and enantioselective synthesis contributed their papers to this volume. They were presented at a symposium on stereoselective synthesis to honour Professor Dr. Dr. h.c. Rudolf Wiecherts achievements in medicinal chemistry research. The symposium was organized by the Schering AG on the occasion of Professor Wiecherts 65th birthday.