Systems Biology and Bioinformatics: A Computational Approach

Emphasizing computational methods, Systems Biology and Bioinformatics provides an introduction to systems biology and its impact on biology and medicine. It reviews basic principles of molecular and cell biology using a system-oriented approach, with a brief description of the high-throughput biological experiments that produce databases. The methods presented include techniques to discover genes, perform nucleotide and amino acid sequence matching, and estimate static gene dynamic pathways. It also explains applications for system-oriented models to predict the behavior of biological systems.