Principles of Pharmacology, The Pathophysiologic Basis of Drug Therapy,2nd Revised edition--------------------------------------------------This primary textbook for a first course in pharmacology offers anintegrated, systems-based, and mechanism-based approach to understandingdrug therapy. Each chapter focuses on a target organ system, beginswith a clinical case, and incorporates cell biology, biochemistry,physiology, and pathophysiology to explain how and why different drugclasses are effective for diseases in that organ system. Over 400 two-colorillustrations show molecular, cellular, biochemical, and pathophysiologicprocesses underlying diseases and depict targets of drug therapy. EachSecond Edition chapter includes a drug summary table presenting mechanism,clinical applications, adverse effects, contraindications, and therapeuticconsiderations. New chapters explain how drugs produce adverse effectsand describe the life cycle of drug development. The fully searchableonline text and an image bank are available on thePoint.