Environmental Factors as Major Contributors to Neurological Disorders

Neurodegeneration involves the gradual loss of structural and functional components of neurons, leading to severe neurological disorders that significantly impact physical and mental health. Recent studies highlight the global concern over neurodegenerative diseases, which are closely linked to environmental factors. Key contributors to these disorders include prenatal and postnatal exposure to industrial toxins, particularly neurotoxic metals such as lead, aluminum, mercury, manganese, cadmium, and arsenic, along with pesticides and metal-based nanoparticles. These contaminants can lead to the formation of senile or amyloid plaques and neurofibrillary tangles (NFTs), which are characteristic of these diseases. Additionally, exposure to solvents is recognized as a significant risk factor.