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The Nature of Information.- The Transmission of Information.- Sets and Combinatorics.- Probability and likelihood.- Randomness and complexity.- Systems, Networks, and Circuits.- Algorithms.- Biology.- to Part II.- The Nature of Living Things.- The Molecules of Life.- Applications.- to Part III.- Genomics.- Proteomics.- Interactomics: Interactions and Regulatory Networks.- Metabolomics and Metabonomics.- Medical Applications.- The Organization of Knowledge.