Intrabodies: Basic Research and Clinical Gene Therapy Applications

Antibodies have long been used in the biomedical sciences as <i>in vitro</i> tools for the identification, purification and functional manipulation of target antigens. They are also being exploited <b>in vivo</b> for diagnostic and therapeutic applications and play an important role in cancer and AIDS research. This book summarizes preclinical studies from laboratories worldwide that have used intrabodies - intracellular antibodies - for gene therapy and research applications.