Aging and the Heart: A Post-Genomic View

Cardiac aging, like aging in general, is a complex process. Numerous cellular and molecular changes contribute to the expression of the multiple phenotypes of aging, "the different faces" of cardiac aging. In this book, the genetic and molecular basis of cardiovascular aging is discussed. The work has been enabled by the availability of the Human Genome Project, and an ever increasing number of animal models as well as new and exciting molecular technologies. It can now be genuinely stated that the unraveling of the underlying basic mechanisms of cardiac aging have begun. The book also includes a comprehensive assessment of the bioenergetic changes that occur in human and animal models of cardiac aging as well as current diagnostic and future therapeutic modalities are undertaken.