The Molecular Biology of Membranes

On February 14, 1977, a symposium entitled "The Molecular Biology of Membranes" was held in New Orleans in honor of Professor David E. Green, whose many contributions in mitochondrial structure and metabolism have influenced and guided research in this important area of biochemistry for many years. The symposium was attended by many former and present-day colleagues, friends, and interested scientists. The contents of this volume represent papers that were delivered at the symposium and other contributions from individuals who have been associates of Professor Green. We wish to thank Plenum Press for their help in making the symposium and publication of this book possible. Sidney Fleischer Youssef Hatefi David MacLennan Alexander Tzagoloff vii Contents Impressions of David E. Green by His Colleagues . . . . . . . . . . . . . . 1 Enzyme Institute Days 13 F. M. Huennekens Perspective for the Mitochondrion 17 David E. Green Chapter 1 Organization of Protein and Lipid Components in Membranes 29 Garret Vanderkooz Chapter 2 Structure of the Mitochondrion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 57 Robert A. Haworth and Douglas R. Hunter Chapter 3 Permeability of Membrane as a Factor Determining the Rate of Mitochondrial Respiration: Role of Ultrastructure . . . . . . . . . . . . . . 75 Jerzy Popinigis Chapter 4 Chemistry of Intrinsic Membrane Protein Complexes: Studies on Complex III and Cytochrome c Oxidase . . . . . . . . . . . . . . . . . . . . . . . 103 Roderick A. Capaldi ix x Contents Chapter 5 Reversible Mitochondrial ATPase as a Model for the Resolution of a 121 Membrane Complex A. E.