Telomerase and Cancer Therapeutics

This book highlights the crucial role of telomerase enzyme in cancertherapeutic. Telomerase activity is repressed in normal human somatic cellsin contrary it is activated in most cancers. Since most tumour cells arereliant on the activity of telomerase to maintain the stability ofpredominant short individual telomeres, inhibition of this enzyme presentsan attractive approach for a mechanism-based anti-cancer therapy.