Extended Protein-Protein Interaction Networks

Online biological databases gain importance in research in biology. These databases usually offer an online search, but the results are just prepared in a textual way. Visualization gives a better view on the data for an easier overall impression of the meaning. When resear-ching in the area of proteins and protein-protein interactions, a computer-based analysis facilitates the process of evaluating the data. However, most existing solutions put their focus on one or at most two proteins including their interaction partners. The InSilico Pro-teomics System project at the FH Oض R&D Center Hagenberg, Austria, aims on integrating public as well as experimentally obtained protein-protein interaction data in one database. PRIMOS (PRotein Interaction and MOlecule Search engine) provides a Web interface for retrieving data from this database. As a result of this work, the Web interface was expanded with a visualization and a computer-based analysis of the data. This work is targeting biologists with technical knowledge who are investigating proteins and protein-protein interactions and software developers in the biological area - e.g. for bioinformatic tools.