Cocrystal of Allopurinol

Gouty arthritis is one of the major problems whose prevalence has doubled in the past decades. Studies have estimated that over 20 million people suffer from gout every year. Allopurinol, the major drug used in the treatment has very poor bioavailability and results in many severe side effects. This book addresses this problem as it has large social implications on the society. One of the recent approaches to explore new pharmaceutical drug is the design of the cocrystals. It has an added advantage that as both the compounds are already approved by the FDA no more drug trial is necessary and hence can be brought to the market in a short period. This work deals with the synthesis and preliminary characterization of cocrystals of Allopurinol. The present work has been carried out over a period of seven months at Sri Sathya Sai Institute of Higher Learning, Prasanthinilayam, India.